Methylocella silvestris BL2


♦ Strain information

Methylocella silvestris BL2 is an aerobic methanotroph originally isolated from an acidic forest soil in Germany. It is the first fully authenticated facultative methanotroph. It grows not only on methane and other one-carbon (C1) substrates, but also on some compounds containing carbon-carbon bonds, such as acetate, pyruvate, propane, and succinate. Here we report the full genome sequence of this bacterium. [Chen 2010]


♦ Genome information

- Lineage: Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Beijerinckiaceae; Methylocella; Methylocella silvestris (NCBI taxonomy ID: 395965)
- NCBI RefSeq accession: NC_011666 (chromosome: 4,305,430 bp)
- Genome paper:
   Chen Y, Crombie A, Rahman MT, Dedysh SN, Liesack W, Stott MB, Alam M, Theisen AR, Murrell JC, Dunfield PF “Complete genome sequence of the aerobic facultative methanotroph Methylocella silvestris BL2Journal of Bacteriology, 192(14):3840-3841 (2010)

♦ Genome browser (NC_011666)


♦ Antibiotics & secondary metabolites

- NC_011666 (chromosome)            


♦ Transcriptome structure

- Visualization of high-density data (e.g. RNAseq, ChIP-chip, tiling microarray) against coordinates on the genome

- Following data set can be visualized by Gaggle Genome Browser (Note: this link downloads large data files (~60-190MB)  at initial access) (Java need to be installed on your computer.)   


♦ Conditional regulons


♦ Metabolic network model


♦ Gene regulatory network model


♦ Phenotype Microarrays

- Phenotype Microarrays testing nearly 2000 cellular phenotypes simultaneously (Biolog PM Technology)